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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF22
All Species:
26.06
Human Site:
S243
Identified Species:
57.33
UniProt:
Q14807
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14807
NP_015556.1
665
73262
S243
A
T
R
L
N
Q
R
S
S
R
S
H
A
V
L
Chimpanzee
Pan troglodytes
XP_510910
679
74714
S243
A
T
R
L
N
Q
R
S
S
R
S
H
A
V
L
Rhesus Macaque
Macaca mulatta
XP_001104365
657
72278
S232
A
T
R
L
N
Q
R
S
S
R
S
H
A
V
L
Dog
Lupus familis
XP_547058
651
71817
L234
S
R
S
H
A
V
L
L
V
K
V
D
Q
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3V300
660
73171
S238
A
T
R
L
N
Q
R
S
S
R
S
H
A
V
L
Rat
Rattus norvegicus
Q5I0E8
657
73037
S235
A
T
R
L
N
Q
R
S
S
R
S
H
A
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZYL5
650
73149
S234
S
T
K
L
N
D
R
S
S
R
S
H
A
V
L
Zebra Danio
Brachydanio rerio
A8WFU8
634
70574
Q234
L
I
K
V
V
K
S
Q
R
G
P
P
H
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
M233
I
F
M
I
K
I
E
M
C
D
T
E
T
N
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46873
699
78760
G294
L
L
Q
D
S
L
G
G
N
T
K
T
I
M
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPC6
894
98404
S259
N
T
K
L
N
T
E
S
S
R
S
H
A
I
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
94.8
90
N.A.
81.3
81
N.A.
N.A.
N.A.
52.3
50.9
N.A.
29.2
N.A.
28.1
N.A.
Protein Similarity:
100
97.5
96.2
93
N.A.
88.7
88.8
N.A.
N.A.
N.A.
69.3
66.1
N.A.
46.1
N.A.
45.7
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
N.A.
80
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
N.A.
93.3
20
N.A.
13.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
0
0
0
10
0
0
0
0
0
0
0
64
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
0
0
10
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
19
0
0
0
0
10
0
0
10
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
10
0
10
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
64
10
0
0
% H
% Ile:
10
10
0
10
0
10
0
0
0
0
0
0
10
10
10
% I
% Lys:
0
0
28
0
10
10
0
0
0
10
10
0
0
0
0
% K
% Leu:
19
10
0
64
0
10
10
10
0
0
0
0
0
0
64
% L
% Met:
0
0
10
0
0
0
0
10
0
0
0
0
0
10
0
% M
% Asn:
10
0
0
0
64
0
0
0
10
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% P
% Gln:
0
0
10
0
0
46
0
10
0
0
0
0
10
0
10
% Q
% Arg:
0
10
46
0
0
0
55
0
10
64
0
0
0
19
0
% R
% Ser:
19
0
10
0
10
0
10
64
64
0
64
0
0
0
0
% S
% Thr:
0
64
0
0
0
10
0
0
0
10
10
10
10
0
10
% T
% Val:
0
0
0
10
10
10
0
0
10
0
10
0
0
55
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _